Antibacterial Antibacterial Activity of 96% Ethanol Extract in Old Leaves of Medang Pirawas (Litsea elliptica Blume) to Staphylococcus aureus Bacteria Antibacterial Activity of 96% Ethanol Extract in Old Leaves of Medang Pirawas (Litsea elliptica Blume) to Staphylococcus aureus Bacteria
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Abstract
Litsea elliptica Blume, is one type of traditional medicinal plant that is widely used by the Indonesian people. This symplisia can be used to treat headaches, fever, stomach ulcers, and also as an insect repellent. Litsea elliptica Blume also has antimicrobial and antioxidant properties. Objective: This study aims to determine whether 96% ethanol extract of Litsea elliptica Blume leaves has antibacterial activity against Staphylococcus aureus bacteria. Methods: This research is a laboratory experiment with descriptive quantitative method conducted in this study to test the antibacterial properties of 96% ethanol extract of Medang Pirawas (Litsea elliptica Blume) against Staphylococcus aureus bacteria. Results: The yield of the thick extract of Litsea elliptica Blume was 19.36 %, and the classes of secondary metabolite compounds found were phenols, flavonoids, saponins, tannins, alkaloids, and terpenoids. The results of the antibacterial activity test of the viscous extract of Litsea elliptica Blume did not show antimicrobial properties against the growth of Staphylococcus aureus, which was characterized by not forming a clear zone on the media. Conclusion: From these results it can be concluded that there is no antibacterial activity of ethanol extract of medang pirawas (Litsea elliptica Blume) leaves against the growth of Staphylococcus aureus bacteria.
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References
Organization WH. World health statistics 2023: monitoring health for the SDGs, sustainable development goals. World Health Organization; 2023. h.80.
Mutsaqof AAN. Sistem pakar untuk mendiagnosis penyakit infeksi menggunakan forward chaining. 2015;4: h.43.
Ballo NDS, Indriarini D, Amat ALSS. Uji Aktivitas Anti Bakteri Ekstrak Etanol Daun Kemangi (Ocimum sanctum L.) Terhadap Pertumbuhan Bakteri Staphylococcus aureus Secara In Vitro. Cendana Medical Journal (CMJ). 2021;9(1): h.83–93.
Muntasir. Widy Susanti Abdulkadir,Andi Ifriany Harun. Muliyadi SSMS, et al. Antibiotik Dan Resistensi Antibiotik. Makasar: Rizmedia Pustaka Indonesia; 2022. h.33–45.
Kemenkes RI. Pedoman pelayanan kefarmasian untuk terapi antibiotik. In: Republik Indonesia: Kementerian Kesehatan. Kementerian Kesehatan RI; 2011. h.22–23.
Marfu’ah N, Ramadhani CA, Hasanah AM. Uji Efektivitas Ekstrak Etanol Daun Bidara (Ziziphus spina-christi L.) terhadap Pertumbuhan Propionibacterium acne. Pharmasipha: Pharmaceutical Journal of Islamic Pharmacy. 2019;3(1): h.31.
Kuspradini H, Sinta S, Silau S, Putri AS. Karakteristik Minyak Atsiri dari Tumbuhan Aromatik Hutan Tropis Jenis Litsea spp dan Potensinya sebagai Antimikroba. Minyak Atsiri: Produksi dan Aplikasinya untuk Kesehatan. 2021; h.53–54.
Wong MH, Lim LF, bin Ahmad F, bin Assim Z. Antioxidant and antimicrobial properties of Litsea elliptica Blume and Litsea resinosa Blume (Lauraceae). Asian Pac J Trop Biomed. 2014;4(5): h.390–391.
Handayani IA, Panca P CB. Skrining Fitokimia dan Penetapan Kadar Tanin Ekstrak Daun Litsea elliptica Blume. Lumbung Farmasi: Jurnal Ilmu Kefarmasian. 2024;5(1): h.55–56.
TS J. Fitokimia Tinjauan Metabolit Sekunder dan Skrining Fitokimia. Vol. 53. J Chem Inf Model. 2019; h.20–45.
Erikania S, Rosalina V. Mikrobiologi Farmasi, Teori dan Praktik. 1st ed. Yogyakata: Deepublish; 2022. h.31–44.